KRT4 anticorps (AA 181-292)
Aperçu rapide pour KRT4 anticorps (AA 181-292) (ABIN6937710)
Antigène
Voir toutes KRT4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 181-292
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Specificité
- Cytokeratin 4 (KRT4) is an intermediate filament protein associated with Cytokeratin 13 (KRT13). It is expressed in suprabasal cells of non-keratinized stratified squamous epithelium of esophagus, cornea, anus, larynx, pharynx and tongue. Decreased expression of KRT4 is associated with head and neck squamous carcinoma. It is helpful in differentiation of squamous cell carcinoma of esophagus origin from that of thyroid origin.
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Réactivité croisée (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Recombinant fragment (around aa 181-292) of human KRT4 protein (exact sequence is proprietary)
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Isotype
- IgG1 kappa
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Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, A549 or A431 cells. Skin, Cervix or Esophagus.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- KRT4 (Keratin 4 (KRT4))
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Autre désignation
- KRT4
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Sujet
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CK4, CYK4, Cytokeratin 4, Keratin 4, Keratin type II cytoskeletal 4, KRT4,Cytokeratin 4 (KRT4)
Cellular localisation: Cytoplasmic and Cell Surface -
Poids moléculaire
- 67kDa
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ID gène
- 3851, 654610, 706527
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UniProt
- P19013
Antigène
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